Last updated: March 9, 2026
Quick Answer
Bryan Johnson tracks 108+ biomarkers through his Blueprint protocol via Labcorp. His Advanced Panel ($375) covers hormones, metabolic health, advanced lipids, and inflammatory markers. He also uses TruDiagnostic for epigenetic age testing (speed of aging: 0.48) and Levels CGM for continuous glucose monitoring. His personal protocol costs ~$2M/year with 30+ doctors, but consumer testing starts at ~$150.
108+
Biomarkers tracked
0.48
Speed of aging
33,537
Total measurements
#1
Rejuvenation Olympics
Bryan Johnson, the tech entrepreneur behind Project Blueprint, has become the most biologically measured person in history. Since 2021, he has spent over $2 million annually on a protocol managed by 30+ doctors, tracking 33,537 biomarkers to reverse his biological age.
His speed of aging is 0.48 — meaning he ages roughly half a year for every calendar year — placing him #1 out of 6,000+ participants in the Rejuvenation Olympics. This guide covers his complete testing protocol, actual lab results, and how to replicate it on any budget.
The 11 Biomarkers Bryan Johnson Tracks for Longevity
At the Don't Die Summit, Bryan Johnson shared the 11 biomarkers he tracks "religiously." These provide 80% of actionable longevity insights and cost under $200 at most labs.
HbA1c
3-month blood sugar average. Bryan targets <5.0%.
hs-CRP
Key inflammation marker. Bryan achieved undetectable levels after HBOT.
LDL Cholesterol
Bryan's LDL averages 35 mg/dL (April 2025 double draw).
HDL Cholesterol
Bryan's HDL averages 55 mg/dL. Higher is protective.
Triglycerides
Bryan's triglycerides average 42 mg/dL (optimal is <100).
Fasting Glucose/Insulin
Tracks via Levels CGM. 94% of readings in 70-125 mg/dL range.
Free Testosterone
Bryan achieved 782 ng/dL naturally after stopping exogenous testosterone.
DHEA-S
Adrenal function and aging marker. Declines with age.
Homocysteine
Bryan's best: 5.1 umol/L. Target is <7 umol/L.
Vitamin D
Immune optimization. Bryan targets 60-80 ng/mL.
Blueprint Testing Products & Costs
Blueprint now sells consumer testing products through partnerships with Labcorp, TruDiagnostic, and Ezra. You don't need $2 million to access Bryan Johnson's testing infrastructure.
Blueprint Basic Panel
~$150
67 biomarkers
Via Labcorp (3,500+ US locations)
CBC, lipid profile, comprehensive metabolic panel, thyroid, liver, kidney function
Blueprint Advanced Panel
$375
108 biomarkers
Via Labcorp
Basic + hormones (testosterone, SHBG, cortisol), metabolic (glucose, insulin, HbA1c), advanced lipids, urinalysis
Speed of Aging Test
$249.50/test
Via TruDiagnostic (at-home kit)
DunedinPACE epigenetic clock, biological age, organ-system ages via SYMPHONYAge
Blueprint x Ezra MRI
$5,995
Via Ezra imaging centers
13 organs scanned, 500+ conditions, brain volume, body composition, aneurysm detection
Bryan Johnson's Complete Blood Panel
The Blueprint Advanced Panel covers 108+ biomarkers across five categories. Here's what Bryan tests and why each category matters for longevity.
Basic Health Markers
Cardiovascular Risk
Hormone Panel
Metabolic Health
Nutritional Status
Bryan Johnson's Actual Blood Test Results (2024-2025)
Bryan Johnson publicly shares his lab results on X (Twitter). These values are from his January 2024 and April 2025 double lab draws, where he draws blood twice to account for measurement variance.
| Biomarker | Bryan's Result | Optimal | Average (age 40-50) |
|---|---|---|---|
| hs-CRP | Undetectable | <0.5 mg/L | 1.0-3.0 mg/L |
| Testosterone | 782 ng/dL | 700-900 ng/dL | 300-500 ng/dL |
| LDL (calculated) | 35 mg/dL | <100 mg/dL | 100-130 mg/dL |
| HDL | 55 mg/dL | >50 mg/dL | 40-50 mg/dL |
| Triglycerides | 42 mg/dL | <100 mg/dL | 100-150 mg/dL |
| Total Cholesterol | 101 mg/dL | <200 mg/dL | 190-210 mg/dL |
| Homocysteine | 5.1 umol/L | <7 umol/L | 8-12 umol/L |
| HbA1c | 4.8% | <5.0% | 5.4-5.7% |
| GGT | 7.5 U/L | <25 U/L | 15-40 U/L |
| VO2 Max | 58.7 mL/(kg*min) | >50 | 30-40 |
Sources: Bryan Johnson's public X posts (January 2024, April 2025). Double lab draws used to measure variance.
Bryan Johnson's Biological Age: Speed of Aging Explained
Bryan Johnson's DunedinPACE speed of aging is 0.48, meaning he ages approximately half a year for every calendar year. At age 48 (born August 22, 1977), he ranks #1 out of 6,000+ participants in the Rejuvenation Olympics, which he founded in 2023.
Epigenetic Testing (TruDiagnostic)
- DunedinPACE: 0.48 (1.0 = average aging)
- Brain age: 42 (chronological: 48)
- Aging rate: 0.69 bio years per calendar year
- Improvement: 14.71% in pace of aging
Other Aging Markers
- VO2 max: 58.7 mL/(kg*min) (top 1.5% of 18-year-olds)
- Telomere length: Increased 2.6% (10.3 to 11.4 kb)
- Telomerase activity: 7.7% (adolescent level)
- Clocks used: DunedinPACE, GrimAge, PhenoAge, Horvath, SYMPHONYAge
Blueprint Protocol Evolution: 2021 to 2026
Bryan Johnson's protocol has changed significantly over 5 years. He has started and stopped multiple interventions based on his biomarker data — a key part of his data-driven approach.
Launched Project Blueprint. Went public with $2M/year protocol. Built team of 30+ doctors.
Protocol refinement. Extensive supplement stack development. Continuous biomarker tracking.
Started/stopped HGH (side effects). First gene therapy (Follistatin). Young blood plasma from son (discontinued). Launched Rejuvenation Olympics. Dr. Oliver Zolman departure.
Stopped exogenous testosterone (achieved 782 ng/dL naturally). Blueprint consumer products launched. Total plasma exchange. Started HBOT protocol (Nov).
HBOT 60-session results: hs-CRP undetectable, 300% VEGF increase. Dropped Rapamycin after 5 years. "Best biomarkers ever" achieved.
Immortals Program launched ($1M/year, 3 slots). Reduced NMN to 6x/week. Added lithium + NDGA. Expanding Blueprint to comprehensive platform.
Bryan Johnson vs Peter Attia: Blood Testing Compared
Both are prominent longevity figures, but their approaches differ significantly. Peter Attia, a physician and author of Outlive, takes a medically conservative, evidence-based approach while Bryan Johnson's protocol is experimental and self-directed.
Bryan Johnson
- 108+ biomarkers via Blueprint
- Emphasizes speed of aging (epigenetic clocks)
- Self-directed, experimental protocol
- Publicly shares all results
- Tracks standard LDL
- $2M/year personal protocol
Peter Attia
- Focused panel, key markers only
- Prioritizes ApoB over standard LDL
- Physician-guided, evidence-based
- Focuses on "four horsemen" of disease
- Uses OGTT (oral glucose tolerance test)
- More accessible approach
How to Test Like Bryan Johnson on a Budget
You don't need $2 million to test like Bryan Johnson. These services offer Blueprint-style comprehensive blood testing at a fraction of the cost, using many of the same biomarkers and lab infrastructure.
| Service | Biomarkers | Price | Unique Feature |
|---|---|---|---|
| Blueprint Advanced Panel | 108+ | $375/test | Bryan Johnson's own protocol. Labcorp partnership. |
| Function Health | 160+ | $365/year | Co-founded by Dr. Mark Hyman. Optimal ranges, clinician review. Labcorp. |
| InsideTracker | 48 | $200-600/test | Used by David Sinclair. InnerAge biological age. DNA add-on $249. |
| Southeast Asia Clinics | 50-100+ | $85-500/test | 60-80% savings vs US. Same biomarkers. Medical tourism option. |
Where to Get Blueprint-Style Blood Tests
Bryan Johnson uses Labcorp (3,500+ US locations) via his Blueprint partnership. Outside the US, comprehensive panels cost 60-80% less while covering the same biomarkers.
iScreen Thailand
Comprehensive panels from ~$85 (฿3,000)
Everlab Australia
50+ markers from A$299 (~$195)
Samitivej Hospital
Executive health packages, Bangkok
Compare All Providers
Browse 50+ blood testing clinics worldwide
Criticisms and Limitations of Bryan Johnson's Approach
While Bryan Johnson's results are impressive, his approach has drawn legitimate criticism from the scientific and medical community.
- N=1 experiment: No control group. The American Council on Science and Health called it "anecdotal evidence at best." Results cannot be attributed to specific interventions.
- Cost barrier: The $2M/year protocol with 30+ doctors is unreplicable. Even the consumer products are premium-priced.
- Discontinued interventions: Rapamycin (5 years, side effects), growth hormone (increased intracranial pressure), young blood transfusions from his son (no measurable benefit).
- Supplement trial issues: Test subjects reported nausea, vomiting, and heartburn from Blueprint supplements (reported by Futurism, NYT).
- Confounding variables: Access to personal chef, 30 doctors, unlimited budget, and full-time health optimization makes results hard to generalize.
Frequently Asked Questions
What blood tests does Bryan Johnson get for longevity?
Bryan Johnson tracks 108+ biomarkers through his Blueprint protocol, tested via Labcorp. His Advanced Panel ($375) covers hormones (testosterone, cortisol, SHBG), metabolic health (glucose, insulin, HbA1c), advanced lipids (ApoB, Lp(a)), inflammatory markers (hs-CRP, IL-6), and nutritional status. He also uses TruDiagnostic for epigenetic age testing and Levels CGM for continuous glucose monitoring.
How often does Bryan Johnson get blood work done?
Bryan Johnson gets comprehensive blood panels every 3-6 months, epigenetic age testing twice per year, and a full-body Ezra MRI annually. He recommends consumers test every 6-12 months as a baseline, or every 3 months if actively optimizing their protocol.
How much does Bryan Johnson spend on blood testing?
Bryan Johnson's personal protocol costs approximately $2 million per year total, with a team of 30+ doctors. However, Blueprint now sells consumer testing: Basic Panel (~$150, 67 biomarkers), Advanced Panel ($375, 108+ biomarkers), Speed of Aging test ($249.50), and Ezra MRI ($5,995). His monthly supplement stack costs ~$361.
What is Bryan Johnson's Blueprint protocol?
Blueprint is Bryan Johnson's comprehensive longevity protocol aimed at reversing biological aging. Started in 2021, it includes a strict 1,950-calorie vegan diet, exercise, sleep optimization, 100+ supplements, and extensive biomarker tracking. Johnson calls himself 'the most biologically measured person ever' with 33,537 biomarkers tracked. His speed of aging is 0.48, meaning he ages roughly half a year for every calendar year.
What is Bryan Johnson's biological age?
Bryan Johnson's speed of aging is 0.48 according to TruDiagnostic's DunedinPACE epigenetic clock, making him #1 out of 6,000+ participants in the Rejuvenation Olympics. At age 48, he ages 0.69 biological years per calendar year. His brain age is 42, and his VO2 max of 58.7 mL/(kg*min) places him in the top 1.5% of 18-year-olds.
Can I do Bryan Johnson's testing protocol on a budget?
Yes. Function Health offers 160+ lab tests for $365/year via Labcorp. InsideTracker provides 48 biomarkers for $200-600 with biological age calculation. Blueprint's own Basic Panel is ~$150 for 67 biomarkers. For maximum value, focus on Bryan's 11 core biomarkers: HbA1c, hs-CRP, LDL, HDL, triglycerides, fasting glucose/insulin, testosterone, DHEA-S, homocysteine, and vitamin D.
Where can I get Bryan Johnson style blood tests?
Blueprint partners with Labcorp (3,500+ US locations) for blood panels. TruDiagnostic provides epigenetic age testing. Ezra offers full-body MRI. Outside the US, comprehensive panels cost 60-80% less: Thailand (iScreen from $85, Samitivej Hospital executive health), Australia (Everlab from A$299), and other Southeast Asian clinics offer similar biomarker coverage.
What biomarkers does Bryan Johnson track monthly?
Bryan Johnson's 11 core biomarkers are: HbA1c, hs-CRP, LDL cholesterol, HDL cholesterol, triglycerides, fasting glucose/insulin, free testosterone (or estradiol for women), DHEA-S, homocysteine, and vitamin D. His Advanced Panel adds 97 more markers including SHBG, cortisol, IGF-1, thyroid panel, ApoB, liver enzymes, kidney function, and electrolytes.
Is Bryan Johnson's longevity protocol worth it?
The full Blueprint protocol costs $2 million annually and requires 30+ doctors, making it impractical for most people. Critics note it's an N=1 experiment with no control group. However, core testing insights are accessible: Blueprint's Advanced Panel ($375) covers 108+ biomarkers, Function Health offers 160+ tests for $365/year, and focusing on the 11 core biomarkers costs under $200 at most labs.
How do I start testing like Bryan Johnson?
Start with Bryan's 11 core biomarkers: HbA1c, hs-CRP, LDL, HDL, triglycerides, fasting glucose/insulin, testosterone, DHEA-S, homocysteine, and vitamin D. Order through Blueprint ($150 Basic Panel), Function Health ($365/year), or InsideTracker ($200-600). Test quarterly. After establishing baselines, add advanced markers like ApoB, Lp(a), and consider epigenetic age testing via TruDiagnostic ($249.50).
