PRP & PRF Facial Rejuvenation

PRP (platelet-rich plasma) and PRF (platelet-rich fibrin) facial treatments at 405 Aesthetics Dallas use the client's own growth factor-rich blood concentrate to stimulate collagen production, accelerate skin renewal, and improve overall skin quality. A small blood draw is processed by centrifuge to produce the concentrated plasma, which is then applied topically after microneedling, micro-injected into the dermis, or used in combination with other treatments. PRP/PRF supports improvement in skin texture, fine lines, skin laxity, and a dull or tired complexion. Fully autologous — no synthetic materials involved.

405 Aesthetics Dallas offers platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) treatments as autologous biological skin rejuvenation protocols, harnessing the client's own concentrated growth factors to support tissue repair and collagen synthesis. The process begins with a small venous blood draw — typically 10–20 mL — which is placed into specialised tubes and centrifuged to separate the blood components by density. The centrifugation process concentrates the platelet fraction in the resulting plasma to approximately three to five times the baseline platelet count found in whole blood. Platelets are the primary reservoir of growth factors including platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-β), vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF-1), and epidermal growth factor (EGF). When introduced into the dermis, these growth factors bind to cell-surface receptors on local fibroblasts, keratinocytes, and endothelial cells, activating signal cascades that upregulate collagen synthesis, accelerate epidermal turnover, and promote neovascularisation. PRF (platelet-rich fibrin) is a second-generation autologous concentrate prepared without anticoagulant additives, resulting in a slowly releasing fibrin matrix that holds growth factors in the tissue for a more sustained delivery period compared to liquid PRP. At 405 Aesthetics Dallas, PRP and PRF are delivered via micro-injection into the superficial dermis across the face — a technique sometimes called the 'vampire facial' — or applied topically in conjunction with microneedling, where the open micro-channels maximise dermal penetration of the concentrate. Combination protocols are also available that pair PRP/PRF application with laser skin therapy for clients targeting both pigmentation and structural skin quality concerns in the same session. Clinical indications at 405 Aesthetics Dallas include age-related skin laxity and fine lines, dull or fatigued complexion, post-inflammatory hyperpigmentation, early acne scarring, and generalised skin quality decline. Because PRP and PRF are derived entirely from the client's own blood, there is no risk of allergic reaction or foreign-body response. Results build progressively over four to eight weeks as the growth factor stimulus takes effect, with a series of two to three sessions recommended for best sustained outcomes.