EZ-Gel PRF — Platelet-Rich Fibrin Treatments

Aura Skin Spa San Francisco uses EZ-Gel PRF (Platelet-Rich Fibrin) — derived from the patient's own blood — as a natural biostimulatory filler and adjuvant to microneedling and injectable treatments. PRF contains concentrated growth factors including PDGF, TGF-β, VEGF, and EGF that drive collagen synthesis and tissue regeneration. Sessions at the Jackson Square clinic run approximately 60 minutes including blood draw and centrifugation preparation.

EZ-Gel PRF (Platelet-Rich Fibrin) at Aura Skin Spa San Francisco is an advanced autologous regenerative treatment that uses the patient's own concentrated blood plasma as a biostimulatory agent. Unlike first-generation PRP (Platelet-Rich Plasma), which is liquid and must be injected immediately, PRF is processed at a lower centrifuge speed to preserve a higher platelet count and produce a fibrin matrix — a natural scaffold that releases growth factors slowly over days to weeks rather than in a single burst. The EZ-Gel protocol begins with a standard blood draw, after which the sample is placed in a centrifuge for approximately ten minutes. The resulting PRF is then warmed briefly to convert it into a gel consistency — the 'EZ-Gel' form — suitable for injection as a natural volumising and regenerative filler, or applied topically immediately after microneedling or laser treatments to enhance absorption and accelerate healing. The growth factor cocktail contained in PRF includes Platelet-Derived Growth Factor (PDGF), Transforming Growth Factor-Beta (TGF-β), Vascular Endothelial Growth Factor (VEGF), and Epidermal Growth Factor (EGF). Together these signals stimulate fibroblast proliferation, new collagen and elastin synthesis, angiogenesis (formation of new blood vessels), and accelerated epidermal turnover. The cumulative effect is progressive skin quality improvement — improved hydration, skin thickness, fine line reduction, and a natural luminosity — that continues to develop for three to six months after treatment. At the Jackson Square clinic, PRF is used in three primary ways: injected into areas of volume loss (under-eye hollows, temples, lips) as an alternative or complement to synthetic fillers; combined with microneedling sessions where it is applied immediately after the Eclipse MicroPen EVO treatment to amplify the healing response; or used alongside laser resurfacing for accelerated recovery and enhanced outcomes. Being autologous — derived from the patient's own blood — there is no risk of allergic reaction or foreign body response, making it suitable for patients who prefer to minimise synthetic products in their aesthetic programme.