Skin Rejuvenation & Bio-Remodelling Injectables

Cityskin Melbourne offers a suite of injectable skin rejuvenation treatments at the Collins Street CBD clinic, including bio-remodelling injections, REJURAN skin boosters containing sodium polynucleotide (PDRN), and collagen-stimulating biostimulator injections. These treatments address skin laxity, loss of luminosity, fine lines, hollowing, and texture irregularities across the face, neck, décolletage, hands, and knees. Sessions are walk-in, walk-out with minimal downtime.

Injectable skin rejuvenation at Cityskin Melbourne's Collins Street clinic encompasses three distinct treatment categories that work at the cellular level to restore skin quality, hydration, and structural support — differing in mechanism from anti-wrinkle injections (muscle relaxation) and dermal fillers (volume replacement) by targeting the dermis itself. Bio-remodelling injections deliver a high-concentration injectable hyaluronic acid preparation that does not fill or sculpt like a conventional filler, but instead disperses through the dermal layer, stimulating collagen type I and III production, elastin synthesis, and adipocyte regeneration at a cellular level. The result is progressive improvement in skin tone, firmness, and hydration across large surface areas — the face, neck, décolletage, hands, and knees can all be treated. The standard protocol involves two sessions spaced four weeks apart, with maintenance recommended every six months. This class of injectable (known generically as bio-remodellers, though Cityskin does not name specific brands due to TGA requirements) has become a cornerstone of skin quality treatment in Australian cosmetic clinics. REJURAN skin boosters use injectable sterile sodium polynucleotide (PDRN) gel — a biocompatible polymer derived from salmon DNA — delivered into the dermal layer through a series of micro-injections. PDRN stimulates fibroblast activity and promotes tissue repair and regeneration at the injection site, improving overall skin quality, periorbital and perioral skin, forehead texture, cheek hydration, and chin appearance. Each session takes 30–45 minutes, and a minimum of two sessions is recommended for optimal results, with injection marks typically fading within three days. Collagen-stimulating biostimulator injections represent a longer-acting approach to restoring facial volume and collagen architecture. This injectable class (biostimulators containing poly-L-lactic acid, not named specifically per TGA) stimulates the body's natural collagen production over two to three months, gradually rebuilding facial volume in areas of atrophy including the temples, cheeks, nasolabial folds, and marionette lines. Results develop slowly and last two years or more, making this option well suited to patients over 35 who have experienced significant volume loss. Cityskin Melbourne's Collins Street clinic offers these injectable rejuvenation treatments on a Tuesday-to-Saturday appointment schedule, with free 30-minute consultations for new patients.