PRP Skin & Hair Rejuvenation

Platelet-rich plasma (PRP) treatments at Dallas Plastic Surgery Institute harness the patient's own growth factor-rich blood concentrate to stimulate skin renewal and support hair follicle health. Blood is drawn, centrifuged to concentrate the platelet fraction, and applied or injected into the treatment area. PRP facial rejuvenation improves skin texture, fine lines, and overall skin quality. PRP scalp injections support hair follicle regeneration for patients experiencing early diffuse hair thinning.

Platelet-rich plasma therapy at Dr. Sam Jejurikar's Dallas practice is an autologous biological treatment that concentrates the patient's own platelets — and the growth factors they carry — into a serum that is then applied to the skin or injected into the scalp to stimulate tissue regeneration. The preparation process begins with a venous blood draw of approximately 10–20 mL. The collected blood is placed in centrifuge tubes and spun at a specific speed and duration to separate the blood components by density: red blood cells settle to the bottom, the platelet-poor plasma floats to the top, and the platelet-rich plasma layer is isolated between them. This fraction contains a platelet concentration approximately three to five times the baseline level found in whole blood. Activated platelets release a suite of growth factors — including platelet-derived growth factor (PDGF), transforming growth factor beta (TGF-β), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), and insulin-like growth factor-1 (IGF-1) — which bind to fibroblast and keratinocyte receptors and upregulate collagen synthesis, epidermal cell turnover, and microvascular development. For facial rejuvenation, PRP is most commonly delivered in conjunction with microneedling — applied to the skin immediately after the micro-channels are created, so that the growth factor concentrate penetrates deeply into the dermis rather than remaining at the surface. PRP can also be micro-injected intradermally as a standalone treatment, sometimes called a 'vampire facial,' targeting the papillary dermis across the full face. Facial PRP is indicated for patients seeking improvement in skin quality, fine lines, skin laxity, dullness, and early atrophic scarring. For scalp use, PRP is injected in a grid pattern across the thinning zones of the scalp, typically at 1 cm intervals and at a depth targeting the subdermal layer adjacent to the hair follicle bulb. The growth factor stimulus supports the anagen (growth) phase of affected follicles and may reduce the premature progression of follicles into catagen (rest) phase that characterises androgenetic alopecia and early diffuse thinning. A series of three to four monthly sessions is standard, followed by maintenance injections every six months. As a fully autologous treatment, PRP carries no risk of allergic reaction or rejection.