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Homocysteine Check

Type

Blood Testing

Biomarkers

1

Duration

30 min

Results

3 days

Simple homocysteine blood test to assess cardiovascular disease, osteoporosis, and Alzheimer's risk.

A homocysteine blood test measures the level of this amino acid in your blood. Homocysteine is a byproduct of protein metabolism that is normally converted into other useful substances with the help of vitamins B6, B12, and folate. When these vitamins are deficient or when genetic variants like MTHFR impair the conversion process, homocysteine can accumulate to harmful levels. Elevated homocysteine (hyperhomocysteinemia) is an independent risk factor for cardiovascular disease, stroke, blood clots, and cognitive decline. It is increasingly recognized in longevity medicine as a modifiable risk factor — levels can often be lowered through B-vitamin supplementation and dietary changes.

Key Details

Biomarkers
1 (homocysteine)
Fasting Required
Yes
Optimal Range
< 10 µmol/L
Sample Type
Blood draw
Turnaround
2–3 business days
Common Use
Cardiovascular risk, methylation status

Who Is This For?

Anyone with a family history of early heart disease or stroke. People with known MTHFR variants who need to monitor their methylation status. Health-conscious individuals incorporating cardiovascular risk markers into their longevity protocol. Those with B12 or folate deficiency being treated and monitored. People with a history of blood clots or recurrent miscarriage.

What's Included

Serum homocysteine level

Preparation Required

Fasting for 10–12 hours before the test is recommended for accurate results. Avoid B-vitamin supplements for 24 hours before testing unless you're specifically monitoring your treatment response.

Biomarkers Tested

1
Homocysteine µmol/L

An amino acid produced during protein metabolism. Elevated homocysteine is an independent risk factor for cardiovascular disease, stroke, and cognitive decline. Levels are lowered by adequate B12, folate, and B6 intake.

Frequently Asked Questions