i-Screen Metabolic/Nutrient Panel - ThyroidChange
Type
Blood Testing
Biomarkers
52
Duration
30 min
Results
48 hours
Comprehensive blood test analyzing metabolic and nutrient levels related to thyroid health.
A thyroid panel evaluates how well your thyroid gland is functioning by measuring the hormones it produces and the pituitary signal that controls it. The thyroid is a butterfly-shaped gland in your neck that regulates metabolism, energy, body temperature, heart rate, and mood. A basic panel measures TSH (the brain's signal to the thyroid) and Free T4 (the main thyroid hormone). Comprehensive panels add Free T3 (the active hormone), reverse T3, and thyroid antibodies (TPOAb, TGAb) that can detect autoimmune conditions like Hashimoto's thyroiditis or Graves' disease. Thyroid dysfunction is extremely common — affecting roughly 1 in 8 women — and often goes undiagnosed because symptoms mimic stress, aging, or depression.
Key Details
Who Is This For?
Anyone experiencing unexplained fatigue, weight changes, hair loss, cold sensitivity, or mood disturbances. People with a family history of thyroid disease or autoimmune conditions. Women planning pregnancy, as thyroid function is critical for fetal brain development. Anyone who has had a 'normal' TSH result but still suspects thyroid dysfunction.
What's Included
Preparation Required
No fasting required for a standalone thyroid panel. If you take thyroid medication (levothyroxine/Synthroid), take your dose after the blood draw, not before — taking it beforehand can temporarily spike T4 levels and skew results. Morning testing is recommended for the most consistent TSH readings, as TSH follows a circadian rhythm and peaks overnight.
Biomarkers Tested
52Measures the number of red blood cells in your blood. Red blood cells carry oxygen from your lungs to every cell in your body. Abnormal levels can indicate anemia, dehydration, or bone marrow disorders.
The iron-rich protein in red blood cells responsible for carrying oxygen throughout your body and returning carbon dioxide to the lungs. Low haemoglobin is the primary marker for anemia and can cause fatigue, weakness, and shortness of breath.
The percentage of your blood volume occupied by red blood cells. It reflects the balance between red blood cell production and loss, helping diagnose anemia, dehydration, and polycythemia.
The average size of your red blood cells. Small cells (microcytic) suggest iron deficiency, while large cells (macrocytic) may indicate vitamin B12 or folate deficiency. Normal-sized cells with low count suggest chronic disease.
The average amount of hemoglobin in each red blood cell. Low MCH indicates that red blood cells carry less oxygen than normal, commonly seen in iron-deficiency anemia.
The average concentration of hemoglobin within each red blood cell. It helps differentiate types of anemia — low MCHC points to iron deficiency, while high MCHC can indicate spherocytosis.
Measures the variation in size among your red blood cells. A high RDW means your red blood cells vary significantly in size, which can help distinguish between different types of anemia.
Measures the total number of white blood cells, your body's primary defense against infection. Elevated levels may indicate infection, inflammation, or immune disorders, while low levels can signal bone marrow problems or autoimmune conditions.
The percentage of white blood cells that are eosinophils. Elevated eosinophil percentages are commonly associated with allergic reactions and parasitic infections.
The percentage of white blood cells that are monocytes. Monocytes are part of the innate immune system and develop into macrophages and dendritic cells in tissues.
The percentage of white blood cells that are lymphocytes, key players in adaptive immunity including antibody production and cell-mediated immune responses.
The percentage of white blood cells that are neutrophils. Neutrophils are the most common WBC type and respond primarily to bacterial infections.
The percentage of white blood cells that are basophils. Basophils play a role in allergic reactions by releasing histamine and other inflammatory mediators.
Measures the number of platelets, small cell fragments essential for blood clotting. Low platelets increase bleeding risk, while high platelets may increase clot risk. Important for monitoring clotting disorders and medication effects.
The primary electrolyte regulating fluid balance and blood pressure. Sodium is essential for nerve impulses and muscle contractions. Abnormal levels can cause confusion, seizures, and cardiac arrhythmias.
A critical electrolyte for heart rhythm, muscle contractions, and nerve function. Both high and low potassium can cause dangerous cardiac arrhythmias. Levels are influenced by kidney function, medications, and diet.
An electrolyte that works with sodium to maintain fluid balance, blood pressure, and acid-base balance. Chloride abnormalities often accompany sodium abnormalities and can indicate dehydration, kidney disease, or metabolic disorders.
A key component of the body's acid-base buffering system. Bicarbonate levels reflect the balance between acids and bases in the blood. Abnormal values help diagnose metabolic acidosis or alkalosis.
A waste product from protein breakdown, processed by the liver and excreted by the kidneys. Elevated urea levels can indicate kidney dysfunction, dehydration, high-protein diet, or gastrointestinal bleeding.
A waste product from normal muscle metabolism, filtered by the kidneys. Blood creatinine levels reflect kidney filtration capacity. Elevated levels may indicate impaired kidney function, dehydration, or excessive muscle breakdown.
An estimated measure of how well your kidneys filter waste from the blood. It's calculated from creatinine levels, age, sex, and race. eGFR is the primary marker used to stage chronic kidney disease.
Bilirubin is a substance produced during the normal breakdown of red blood cells. High levels can lead to jaundice and indicate liver or bile duct problems.
An enzyme found in the liver, heart, and muscles. While less liver-specific than ALT, elevated AST can indicate liver damage, heart attack, or muscle injury. The AST/ALT ratio helps distinguish between different liver conditions.
A liver enzyme that helps convert proteins into energy. ALT is found primarily in the liver, making it a highly specific marker for liver damage. Elevated levels may indicate hepatitis, fatty liver disease, or medication-related liver injury.
A liver enzyme sensitive to alcohol use and bile duct problems. GGT is often the first liver enzyme to rise when bile ducts are blocked. Combined with ALP, it helps determine whether elevated ALP is from liver or bone.
An enzyme found in the liver, bones, kidneys, and digestive system. Elevated ALP can indicate bile duct obstruction, liver disease, or bone disorders. It's normally higher in children and during pregnancy due to bone growth.
Measures the combined amount of albumin and globulin proteins in your blood. These proteins are essential for fighting infections, blood clotting, and transporting substances throughout the body.
The most abundant protein in blood, produced by the liver. Albumin maintains blood volume and pressure, and transports hormones, vitamins, and drugs. Low levels indicate liver disease, kidney disease, malnutrition, or chronic inflammation.
A group of proteins in blood including antibodies (immunoglobulins), transport proteins, and enzymes. Elevated globulin can indicate chronic infection, inflammation, or blood cancers. Calculated by subtracting albumin from total protein.
Involved in over 300 enzymatic reactions including energy production, muscle function, and nerve signaling. Magnesium deficiency is common and associated with muscle cramps, anxiety, insomnia, and increased cardiovascular risk.
An enzyme found in nearly all body tissues. Elevated LDH is a general marker of tissue damage and can indicate liver disease, heart attack, anemia, muscle injury, or certain cancers.
A mineral essential for bone formation, energy metabolism (ATP), and acid-base balance. Phosphate levels are inversely related to calcium and regulated by parathyroid hormone and vitamin D.
The most abundant mineral in the body, essential for bone health, muscle contraction, nerve function, and blood clotting. Blood calcium is tightly regulated by parathyroid hormone and vitamin D. Abnormal levels can indicate parathyroid disorders.
Calcium adjusted for albumin levels to provide a more accurate measure of physiologically active calcium. Important because total calcium can appear falsely low when albumin is low, even if actual calcium is normal.
If too much urate is produced or not enough is excreted, it can accumulate and lead to gout – an inflammation that occurs in joints.
If you have diabetes your body doesn't process glucose effectively.
The best indicator of overall vitamin D status. Vitamin D is essential for calcium absorption, bone health, immune function, and mood regulation. Deficiency is extremely common, especially in northern latitudes, and linked to increased disease risk.
A mineral essential for oxygen transport (in hemoglobin), energy production, and immune function. Serum iron measures the amount circulating in blood, but ferritin and TIBC provide a more complete picture of iron status.
Transferrin is a protein that binds and transports iron in the blood. Abnormal levels can indicate iron metabolism disorders.
The percentage of transferrin (iron-transporting protein) that is carrying iron. Calculated from serum iron and TIBC. Low saturation indicates iron deficiency; high saturation may indicate hemochromatosis (iron overload).
The primary iron storage protein. Ferritin reflects total body iron stores and is the first marker to drop in iron deficiency. However, ferritin also rises with inflammation, infection, and liver disease, which can mask true iron deficiency.
Red blood cell testing provides a measurement equivocal to intracellular levels, and is therefore more insightful than a regular zinc blood test.
Red blood cell testing provides a measurement equivocal to intracellular levels, and is therefore more insightful than a regular serum blood test.
Active vitamin B12 is the biologically active form of vitamin B12 that is essential for many physiological processes in the body, including the production of red blood cells, DNA synthesis, and nerve function.
Leptin is a mediator of long-term regulation of energy balance, suppressing food intake and thereby inducing weight loss. Because leptin reduces food intake and body weight, the coexistence of elevated leptin levels with obesity is widely interpreted as evidence of “leptin resistance.”
A highly sensitive test for low-grade chronic inflammation linked to cardiovascular disease risk. Lower hs-CRP values are associated with better cardiovascular outcomes.
Creatinine is a waste product that your body makes when you use your muscles or when your body digests meat. Healthy kidneys remove creatinine from your blood, and it leaves your body in your urine. This test can find out whether your kidneys are working normally or to see if treatment for kidney disease is working.
Iodine is an essential trace element and an integral component of thyroid hormones. Thyroid hormones are required for normal growth and development of tissues and maturation of our bodies. Approximately 80% of iodine is excreted in the urine, making it a good marker of the previous day's intake.
Iodine levels can be adjusted for urine dilution using creatinine. This adjustment accounts for differences in urine volume or concentration and allows for a more accurate assessment of iodine status.
The primary screening test for thyroid function. TSH is produced by the pituitary gland to regulate thyroid hormone production. High TSH indicates an underactive thyroid (hypothyroidism), while low TSH suggests an overactive thyroid (hyperthyroidism).
The unbound, active form of the main thyroid hormone T4. Free T4 directly reflects thyroid gland output and is used alongside TSH to diagnose and monitor thyroid disorders.
The active form of thyroid hormone responsible for regulating metabolism, energy, and body temperature. Free T3 is converted from T4 in tissues and is three to four times more potent than T4.
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- Category
- Diagnostic
- Sample Type
- Blood draw
- Duration
- 30 min
- Results
- 48 hours
i-Screen
i-Screen is an Australian health service offering blood testing and analytics to help individuals understand and monitor their health through personalized online dashboards.