Pancreatic Insufficiency Check

Stool test to assess pancreatic exocrine function.

Pancreatic enzyme tests measure amylase and lipase — enzymes produced by the pancreas that help digest carbohydrates and fats. When the pancreas is inflamed or damaged (pancreatitis), these enzymes leak into the bloodstream in elevated quantities. Lipase is considered the more specific and sensitive marker for pancreatitis, often remaining elevated longer than amylase. These tests are primarily used to diagnose acute pancreatitis, monitor chronic pancreatitis, and evaluate abdominal pain of unclear origin. Amylase is also produced by the salivary glands, so elevated amylase alone can sometimes indicate non-pancreatic conditions.