Executive Physical — Full-Body Longevity Assessment

Next Health Boston's Executive Physical ($14,500) is the most comprehensive longevity assessment available at the clinic, designed for patients who want a full-spectrum picture of their biological age and disease risk. The package includes 500+ biomarkers, a TrueAge epigenetic biological age test, Galleri multi-cancer early detection, a 75-minute full-body MRI, chest CT, CT calcium score for coronary artery disease risk, InBody composition analysis, a Total Tox Burden toxin screen, and in-depth provider consultations to interpret findings and build a personalised health plan.

The Executive Physical at Next Health Boston represents the most thorough single-appointment health evaluation the clinic offers — a multi-modal longevity assessment built for patients who want to go well beyond a standard annual physical and understand their body at a biological rather than chronological level. At $14,500, the programme covers more than 500 biomarkers across blood chemistry, immunology, endocrinology, metabolic health, and genetics. This panel is orders of magnitude broader than what a conventional primary care visit orders, capturing markers such as LP(a) for hereditary cardiovascular risk, homocysteine, fibrinogen, advanced lipid fractions, inflammatory cytokines, comprehensive thyroid function, sex hormones and their metabolites, heavy metals, and micronutrients — all in a single coordinated draw. The TrueAge epigenetic test analyses DNA methylation patterns to calculate a biological age separate from chronological age — a metric increasingly recognised in longevity research as more predictive of health outcomes than birthdate alone. Patients with a biological age younger than their chronological age have measurable evidence that their lifestyle and health interventions are working; those with accelerated epigenetic ageing gain a motivating data point and a baseline against which to measure future improvement. The Galleri multi-cancer early detection test is a liquid biopsy that screens for cell-free DNA signals associated with more than 50 cancer types in a single blood draw. It is designed to detect cancers at earlier stages than symptoms typically appear, making it a meaningful addition for patients over 40 or those with family history of cancer. Imaging forms the diagnostic backbone of the Executive Physical. The 75-minute full-body MRI covers the brain, spine, abdomen, pelvis, and musculoskeletal system, identifying structural abnormalities, organ lesions, and incidental findings that would not appear in blood work. The chest CT adds pulmonary detail, while the CT calcium score quantifies calcified plaque in the coronary arteries — one of the strongest independent predictors of future cardiovascular events. The InBody composition analysis provides a precise measurement of lean mass, fat mass, visceral fat, and hydration levels, establishing a body composition baseline that can track change over time. The Total Tox Burden screen assesses exposure to common environmental toxins including heavy metals, mycotoxins, and organic chemicals. All findings across every modality are reviewed by a Next Health provider in a dedicated consultation, where results are integrated into a personalised health and longevity plan. The Boston location at Chestnut Hill serves patients from across Greater Boston, including the Back Bay, Beacon Hill, Cambridge, Newton, Brookline, and the North Shore.