Hormone Testing & Optimisation

Next Health Boston offers layered hormone assessment from a baseline blood panel through the gold-standard DUTCH Hormone Plus urine test, which profiles 30+ sex hormones, cortisol rhythm, melatonin, and oxidative stress markers. The at-home DUTCH test ($750) ships within 2–3 days and returns results in 2–3 weeks for specialist review. For patients pursuing hormone optimisation, the clinic offers bioidentical hormone therapy via creams, tablets, or pellets alongside quarterly monitoring and provider consultations through its Medicine 4.0 membership.

Hormone assessment at Next Health Boston spans two distinct methodologies — standard blood serum testing and the more comprehensive DUTCH (Dried Urine Test for Comprehensive Hormones) protocol — giving patients and their providers a multi-dimensional view of endocrine function that a single blood draw cannot capture alone. The Baseline Test ($349) includes a hormone overview within its 50+ biomarker panel, covering testosterone (total and free), estradiol, progesterone, DHEA-S, and TSH as a thyroid proxy. This level of testing is appropriate for patients screening for general hormonal imbalance or starting an initial health programme, and the results provide enough data to determine whether more granular testing is warranted. The DUTCH Hormone Plus ($750) is an at-home urine collection test that provides a substantially richer picture. It reports on 30+ biomarkers across the full steroid hormone cascade: estrogen (E1, E2, E3) and their metabolites via the 2-OH, 4-OH, and 16-OH pathways; progesterone metabolites; testosterone and its conversion products; and adrenal hormones including cortisol and cortisone at four time points across the day, mapping the diurnal cortisol rhythm in a way that a single morning blood draw cannot. Melatonin is included as a sleep and circadian health indicator, and oxidative stress markers (8-OHdG) add a cellular damage dimension. The at-home collection kit ships within 2–3 business days of ordering; dried urine samples are returned to the lab and results are delivered in 2–3 weeks, with a provider consultation scheduled to interpret findings. For patients whose results indicate a need for hormone optimisation, Next Health Boston offers a bioidentical hormone therapy programme. Delivery options include topical creams, oral tablets, or sub-dermal pellets — with pellets typically lasting 3–6 months per insertion. The programme requires a Medicine 4.0 membership, which bundles quarterly laboratory monitoring and quarterly provider consultations, creating a structured follow-up framework that ensures safety and efficacy over time. The Chestnut Hill location serves patients from throughout Greater Boston including the Back Bay, Brookline, Cambridge, Newton, and Wellesley.