EBOO Ozone Therapy

Next Health Boston offers EBOO (Extracorporeal Blood Oxygenation and Ozonation), an advanced ozone therapy protocol confirmed for the Chestnut Hill flagship. In an EBOO session, blood is drawn out, passed through a medical-grade ozone and oxygen mixture in an extracorporeal circuit, then returned — a process that saturates red blood cells with ozone and removes circulating toxins and inflammatory compounds. It is used in the longevity space to support immune function, energy, and systemic detoxification.

EBOO (Extracorporeal Blood Oxygenation and Ozonation) is one of the most advanced ozone therapy protocols available and is confirmed to be offered at Next Health Boston's Chestnut Hill location. Unlike simpler ozone modalities such as ozone sauna or rectal insufflation, EBOO uses an extracorporeal circuit — drawing blood from one arm, passing it through a specialised filter and ozone/oxygen mixture outside the body, and returning the treated blood via the opposite arm — a closed-loop process that more closely resembles plasmapheresis in its engineering than a conventional IV infusion. The ozonation step saturates red blood cells with reactive oxygen species (ROS), which are hypothesised to trigger a cascade of adaptive antioxidant responses in the body — a concept sometimes called oxidative pre-conditioning. Simultaneously, the filtration component removes lipid deposits, toxins, and inflammatory debris from circulating blood, which proponents suggest contributes to systemic detoxification effects. The combined oxygenation and filtration steps differentiate EBOO from Major Autohemotherapy (MAH), the older ozone IV protocol that treats a fixed volume of blood ex vivo before reinfusion. In the longevity and functional medicine space, EBOO is used to support immune modulation, energy and mitochondrial function, cardiovascular health, and systemic detoxification. It is often combined at Next Health with other IV therapies, NAD+ infusions, or hyperbaric oxygen for patients pursuing structured longevity protocols. Sessions run approximately 60 minutes and require an intake assessment before starting. Next Health Boston's decision to offer EBOO at the Chestnut Hill flagship reflects its positioning as the most advanced domestic Next Health site, with exclusive technologies not available at all locations in the network. Patients from the Back Bay, Brookline, Newton, Cambridge, and the wider Greater Boston area can access this therapy at the Chestnut Hill centre, open seven days a week.