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DHEA-S Blood Test

Type

Blood Testing

Biomarkers

5

Duration

30 min

Results

4 days

Assess adrenal function and hormonal balance with our DHEA-S Blood Test.

The DHEA-S blood test is important for assessing the function of the adrenal glands and the balance of sex hormones in the body. DHEA-S (Dehydroepiandrosterone Sulfate) is a hormone produced by the adrenal glands, serving as a precursor to androgens and estrogens, the male and female sex hormones. By measuring DHEA-S levels, you gain insights into various health conditions related to hormonal imbalances and adrenal function. One of the primary reasons for conducting a DHEA-S test is to diagnose adrenal gland disorders. Conditions such as adrenal insufficiency or adrenal hyperplasia can significantly impact DHEA-S levels. Low levels of DHEA-S might indicate adrenal insufficiency, where the adrenal glands do not produce adequate hormones. Elevated levels can suggest adrenal hyperplasia, a condition characterised by excessive hormone production due to gland enlargement. The test is also essential for evaluating symptoms of hormonal imbalances. Abnormal levels of DHEA-S can be associated with conditions like polycystic ovary syndrome (PCOS) in women, which often presents with symptoms such as irregular menstrual cycles, excessive hair growth, and acne. By measuring DHEA-S, you can better understand the hormonal dynamics contributing to your symptoms and work on treatment plans with your doctor.

Key Details

Biomarkers
4–12 hormone markers
Fasting Required
Not required, but morning draw recommended
Sample Type
Blood draw
Turnaround
2–5 business days
Timing Note
Morning draw for accurate testosterone/cortisol

Who Is This For?

Men over 30 experiencing low energy, reduced libido, difficulty building muscle, or mood changes. Women with irregular periods, fertility concerns, or perimenopausal symptoms. Anyone experiencing unexplained fatigue, weight gain, sleep disruption, or mood swings. Athletes interested in optimizing recovery and performance through hormonal insights.

What's Included

Testosterone (total and/or free)
Estradiol (E2)
Sex hormone-binding globulin (SHBG)
Cortisol
DHEA-S
FSH and LH (gonadotropins)
Progesterone (if female panel)
Prolactin (if comprehensive)

Preparation Required

Fasting for 10–12 hours before your appointment is recommended for accurate results (water is fine). Avoid alcohol for 24 hours and intense exercise for 12 hours before the blood draw. Morning appointments are ideal for consistent hormone and glucose readings. The blood draw typically takes 5–10 minutes.

Biomarkers Tested

5
DHEA-S µg/dL

Precursor to other hormones

Dehydroepiandrosterone sulfate (DHEA-S) µg/dL

The sulfated, stable form of DHEA with a long half-life, making it the preferred test for adrenal androgen production. DHEA-S is the most abundant circulating steroid hormone and a key longevity biomarker.

Estradiol (E2) pg/mL

The most potent and prevalent form of estrogen. In women, estradiol regulates the menstrual cycle, fertility, and bone density. In men, it's produced from testosterone and plays roles in bone health and libido. Levels vary significantly with age and menstrual cycle.

SHBG (Sex Hormone-Binding Globulin) nmol/L

A protein that binds and transports sex hormones (testosterone, estrogen) in the blood. High SHBG reduces the amount of free, active hormones available. SHBG increases with age, thyroid hormones, and estrogen; decreases with obesity and insulin resistance.

Cortisol µg/dL

The primary stress hormone, produced by the adrenal glands. Cortisol regulates metabolism, immune response, blood pressure, and the sleep-wake cycle. Chronically elevated cortisol from stress contributes to weight gain, immune suppression, and metabolic dysfunction.

Available at 29 locations

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Price
£40.00 £50.00

Subscription plans and discounts (up to 20% off)

Category
Diagnostic
Sample Type
Blood draw
Duration
30 min
Results
4 days
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