TruAge Epigenetic Biological Age Testing

TruAge epigenetic biological age testing through TruDiagnostic, available as a kit consultation at Radiant Health SF in San Francisco. The test analyses DNA methylation patterns from a dried blood spot to calculate biological age, DunedinPACE speed-of-aging score, and SYMPHONYAge organ-system scores across 11 body systems. Results cover 75 or more longevity biomarkers. Consultation with a naturopathic physician to interpret findings and build a personalised protocol is included.

Radiant Health SF serves as a San Francisco access point for TruDiagnostic's TruAge epigenetic testing platform — one of the most clinically validated biological age assessments available outside of research settings. The test is based on next-generation DNA methylation sequencing: the laboratory measures the methylation state at hundreds of thousands of cytosine-guanine (CpG) sites across the genome using a dried blood spot sample collected at home and mailed back in the provided collection kit. The methylation signature is then processed through several validated epigenetic clocks to produce a suite of biological age outputs. The core output is a biological age estimate — the patient's epigenetic age relative to chronological age — giving a quantified view of how the body has aged biologically, independent of calendar years. Younger biological age relative to chronological age may be associated with better long-term health outcomes. The DunedinPACE score is a complementary metric that estimates the current speed of biological aging: a pace below 1.0 indicates slower-than-average aging, while a value above 1.0 suggests faster aging relative to the population. This is particularly useful for tracking the real-time impact of longevity interventions such as BHRT, NAD+ therapy, peptide protocols, or lifestyle changes. The SYMPHONYAge report maps biological aging across 11 organ and system clocks — brain, heart, kidney, liver, lung, immune, musculoskeletal, metabolic, inflammatory, hormonal, and skin — providing a granular view of which body systems are aging fastest and informing a targeted intervention plan. Over 75 longevity biomarkers are included in the combined report. Results are reviewed in a follow-up consultation with one of the clinic's naturopathic doctors, who uses the data alongside hormone panel results and micronutrient findings to design a comprehensive longevity protocol. Retesting annually or semi-annually allows patients to track biological age change in response to their programme.