PRP Prolotherapy — Tendons, Ligaments & Joints

Platelet Rich Plasma (PRP) Prolotherapy using the patient's own concentrated platelets to stimulate healing in injured tendons, ligaments and joints. Effective for knee pain, shoulder injuries, tennis elbow, plantar fasciitis, back pain and joint instability.

PRP Prolotherapy at Singapore Paincare Center is a regenerative medicine procedure that harnesses the body's own healing capacity to repair damaged musculoskeletal tissue. The treatment is designed for patients with chronic or subacute pain in tendons, ligaments and joints who have not achieved lasting relief through physiotherapy, medication or conventional injections. The procedure begins with a blood draw from the patient — typically 15 to 30 mL — which is then placed into a centrifuge to separate the platelet-rich plasma from red blood cells and other components. The resulting PRP preparation contains a concentration of platelets five to ten times higher than normal blood, along with a rich supply of growth factors including PDGF, TGF-β, VEGF and IGF-1. These growth factors are essential signals that activate fibroblasts, tenocytes and chondrocytes to lay down new collagen and tissue matrix, accelerating the natural healing response in damaged structures. Using image guidance where appropriate, the physician injects the PRP precisely into the site of injury — whether that is a partially torn tendon, a stretched or torn ligament, an arthritic joint surface, or an area of chronic inflammation. For larger or more complex injuries, multiple injection points may be used within a single session. Common conditions treated with PRP Prolotherapy at Singapore Paincare Center include knee osteoarthritis and meniscus injuries, shoulder rotator cuff tendinopathy and tears, tennis elbow (lateral epicondylitis) and golfer's elbow (medial epicondylitis), chronic plantar fasciitis and Achilles tendinopathy, ankle ligament instability, hip labral and tendon pain, and chronic lower back and neck pain originating from soft-tissue or facet joint degeneration. PRP is autologous — drawn from and returned to the same patient — making the risk profile very low. The main side effects are localised soreness and swelling at the injection site lasting two to three days, which is a natural part of the healing response. The chance of local infection is less than 1%. Patients typically undergo a course of two to four sessions spaced four to six weeks apart, with meaningful improvement in pain and function expected within six to twelve weeks of the first injection. Singapore Paincare Center's pain physicians bring specialist expertise in image-guided injection techniques, ensuring accurate placement for maximum therapeutic effect.