Vyšetření ledvin — Kidney Panel

Renal function assessment at SYNLAB Brno measuring creatinine, urea, sodium, and potassium with calculated eGFR for chronic kidney disease staging. At 218 CZK (~9 EUR), a focused kidney screen suited for diabetes monitoring, hypertension follow-up, or general renal health baseline.

This panel provides the essential biomarkers for assessing kidney function and detecting chronic kidney disease (CKD). Creatinine, a breakdown product of muscle creatine phosphate metabolism, is filtered by the kidneys at a relatively constant rate. When combined with age, sex, and ethnicity in the CKD-EPI equation, serum creatinine yields the estimated glomerular filtration rate (eGFR) — the standard metric for kidney function staging under KDIGO international guidelines. CKD staging follows a six-tier system: Stage 1 (normal function, eGFR 90 or above), Stage 2 (mildly decreased, 60-89), Stage 3a (mildly-moderately decreased, 45-59), Stage 3b (moderately-severely decreased, 30-44), Stage 4 (severely decreased, 15-29), and Stage 5 (kidney failure, below 15). An eGFR below 60 sustained for three or more months defines CKD stage 3 or worse, affecting approximately 10% of adults over 65 across Central Europe. Urea (blood urea nitrogen) provides complementary information. While urea rises in renal impairment, it is also influenced by hydration status, dietary protein intake, gastrointestinal bleeding, and catabolic states. The creatinine-to-urea ratio helps clinicians distinguish between pre-renal causes (dehydration, heart failure) and intrinsic renal parenchymal disease. Electrolytes — sodium and potassium — are tightly regulated by the kidneys. Hyperkalaemia (elevated potassium) is the most immediately dangerous electrolyte abnormality in CKD, capable of triggering life-threatening cardiac arrhythmias and serving as a common indication for emergency dialysis. Sodium disturbances reflect fluid balance and hormonal regulation. Regular kidney function monitoring is clinically indicated for patients with diabetes (the leading cause of CKD worldwide), hypertension (the second leading cause), established cardiovascular disease, and those taking potentially nephrotoxic medications including NSAIDs, ACE inhibitors, angiotensin receptor blockers, and aminoglycoside antibiotics. For medical tourists from Austria or Slovakia visiting Brno, this focused renal panel costs roughly one-third of equivalent testing in Vienna. The Titanium collection point near Brno main station makes it easy to incorporate into a day trip. Blood draw and serum separation are included. Results within two business days.