Hladina vitamínu D — Vitamin D Test

Serum 25-hydroxyvitamin D measurement at SYNLAB Brno assessing total vitamin D status from dietary intake and sun exposure. At 470 CZK (~19 EUR), essential screening at Central European latitudes — Brno sits at 49.2°N where UV-B exposure is inadequate for cutaneous synthesis from October through March.

25-hydroxyvitamin D (calcidiol) is the accepted clinical standard for evaluating vitamin D status, reflecting the combined contribution of dietary intake, supplementation, and cutaneous synthesis from ultraviolet-B radiation. The test measures total 25(OH)D, encompassing both D2 (ergocalciferol, from plant sources) and D3 (cholecalciferol, from animal sources and sunlight). Deficiency is defined as serum levels below 50 nmol/L (20 ng/mL), insufficiency as 50-75 nmol/L, and optimal status as 75-125 nmol/L. At Brno's latitude (49.2°N), effective cutaneous vitamin D synthesis occurs only from approximately late March through September — during the remaining months, the solar zenith angle is too low for UV-B photons to reach the skin in sufficient quantities for meaningful cholecalciferol production. Supplementation is necessary for the majority of residents and visitors during the winter half of the year. Vitamin D receptors are expressed in virtually every human tissue type. Beyond the classical role in intestinal calcium absorption and bone mineralisation, adequate vitamin D status is associated with immune modulation, skeletal muscle strength, cardiovascular health, and psychological wellbeing. Chronic deficiency triggers secondary hyperparathyroidism, which mobilises calcium from bone and accelerates osteoporotic bone loss — a particular concern for the ageing population across Central Europe. Population-level studies consistently demonstrate that 60-80% of Central European adults are vitamin D deficient during winter months. Testing in late winter (February-March) captures the annual nadir and provides the most clinically actionable information. For visitors from Austria or southern Germany — who share the same latitude band and the same seasonal UV-B deficit — testing during a Brno visit is just as relevant as testing at home, at a substantially lower cost. The Moravian diet historically included more freshwater fish than the Bohemian diet, but dietary vitamin D intake remains insufficient across the Czech Republic without supplementation or fortification. At 470 CZK (~19 EUR), this test is priced comparably to German laboratories but is accessible without a physician referral. Blood draw and serum separation are included. Results within two business days.