YEARS Core®

Comprehensive longevity diagnostic program with 87 lab biomarkers and 25 functional examinations. Blood, urine samples. Foundation program for early disease detection and prevention. Biomarkers tested: Complete Blood Count (CBC) - red/white blood cells, hemoglobin, hematocrit, platelets, MCV, MCH, MCHC; Organ Functions - liver enzymes (AST, ALT, GGT, ALP), kidney function (creatinine, eGFR, BUN, urea); Lipid Metabolism - total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides, ApoB (apolipoprotein B), oxidized LDL; Glucose Metabolism - fasting glucose, HbA1c (3-month blood sugar average), HOMA-Index (insulin resistance), fasting insulin; Thyroid Hormones - TSH (thyroid stimulating hormone), Free T3, Free T4; Inflammatory Markers - hs-CRP (high-sensitivity C-reactive protein), ESR (erythrocyte sedimentation rate); Cardiovascular - NT-proBNP (heart failure marker), blood pressure monitoring; Vitamins & Minerals - Vitamin D (25-OH), Ferritin (iron storage), electrolytes (sodium, potassium, calcium, magnesium); Tumor Markers - PSA (prostate-specific antigen for men), CA 125 (ovarian cancer marker for women); Additional Markers - uric acid, albumin, total protein, bilirubin, LDH. Includes personalized health report, prevention plan, on-demand physician support, and optional coaching sessions. Functional exams include cardiovascular assessment, body composition analysis, vital signs monitoring. Results delivered in visual, actionable format emphasizing prevention before symptom onset.

Advanced longevity diagnostic program with 120 lab biomarkers, 25+ functional examinations, whole-body MRI, and multi-cancer detection screening. Blood, urine, stool samples. Enhanced program building on Core® with advanced aging markers and comprehensive cancer screening. Biomarkers tested: ALL YEARS Core® biomarkers (87 markers) PLUS: Hormone Panel - DHEA-S (dehydroepiandrosterone sulfate, adrenal function), total testosterone, free testosterone, estradiol (E2), progesterone, SHBG (sex hormone binding globulin), LH (luteinizing hormone), FSH (follicle stimulating hormone), prolactin, cortisol (stress hormone); Advanced Vitamins - Vitamin B12 (methylmalonic acid), Vitamin A (retinol), Vitamin K2 (menaquinone), Vitamin E (tocopherol); Minerals - Selenium, Zinc, Copper, Iodine; Advanced Lipids - Lipoprotein(a) [Lp(a)], small dense LDL particles, remnant cholesterol; Growth Factors - IGF-1 (insulin-like growth factor), IGFBP-3 (binding protein); Cardiovascular Advanced - Lp-PLA2 (lipoprotein-associated phospholipase A2), Interleukin-6 (IL-6), Homocysteine (cardiovascular disease risk); Metabolic - Leptin (appetite regulation), adiponectin; Omega Fatty Acids - Omega-3 Index, Omega-6/Omega-3 ratio, EPA, DHA, AA. Additional Services: Whole-Body MRI - radiation-free imaging detecting tumors (70+ solid tumor types), vascular issues, metabolic liver disease, spinal problems; Liquid Biopsy - non-invasive multi-cancer early detection screening with 96-99% specificity, 65-89% sensitivity; Year-round concierge medical support; 1 physician check-in annually; Initial nutrition and performance coaching session. Most comprehensive mid-tier program for serious longevity optimization and cancer prevention.

Ultimate longevity diagnostic program with 230 lab biomarkers, 25+ functional examinations, whole-body MRI, multi-cancer detection, genomics, microbiomics, and epigenomics. Blood, urine, stool, saliva, living cell samples. Most comprehensive longevity program combining ALL diagnostic modalities. Biomarkers tested: ALL YEARS Evolve® biomarkers (120 markers) PLUS: Autoimmune Markers - ANA (antinuclear antibodies), RF (rheumatoid factor), anti-CCP, anti-TPO (thyroid peroxidase), anti-thyroglobulin, celiac disease markers (anti-tTG, anti-DGP); Infection Screening - Hepatitis B (HBsAg, anti-HBs, anti-HBc), Hepatitis C (anti-HCV), HIV (antibody/antigen test), EBV (Epstein-Barr virus), CMV (cytomegalovirus); Advanced Cytokines - TNF-alpha (tumor necrosis factor), IL-1beta, IL-8, IL-10, interferon-gamma; Oxidative Stress - TMAO (trimethylamine N-oxide), CoQ10 (coenzyme Q10), glutathione, 8-OHdG (DNA damage marker), malondialdehyde (MDA); Immunoglobulins - IgG subclasses (IgG1, IgG2, IgG3, IgG4), IgA, IgM, IgE; Amino Acids - essential amino acids profile (leucine, isoleucine, valine, lysine, methionine, phenylalanine, threonine, tryptophan), non-essential amino acids (arginine, glutamine, glycine, proline, tyrosine); Advanced Nutrients - Nicotinamide (NAD+ precursor), Vitamin B1 (thiamine), B2 (riboflavin), B6 (pyridoxine), B9 (folate), biotin, pantothenic acid; Heavy Metals - lead, mercury, cadmium, arsenic; Bone Health - osteocalcin, CTX (bone turnover marker), vitamin K status. Advanced Diagnostics: Medical Genomics - whole exome/genome sequencing analyzing 170+ disease risk genes (cancer susceptibility, cardiovascular disease, Alzheimer's, metabolic disorders), 150+ pharmacogenomics markers (drug metabolism, adverse reaction risks); Microbiomics - comprehensive gut bacteria and fungi analysis, diversity scores, pathogen detection, dysbiosis markers; Epigenomics - biological age assessment via DNA methylation patterns, epigenetic aging clocks, age acceleration metrics; YEARS Performance Battery - advanced functional testing; Biological Specimen Preservation - cryopreservation of 70 blood samples for future regenerative medicine applications. Premium Support: Year-round concierge support with 10-hour annual retainer; 3 physician check-ins annually; Monthly coaching sessions (nutrition, performance, lifestyle). Most advanced longevity program globally for comprehensive health optimization, disease prevention, and lifespan extension.